- Potent Anti Catabolic Reduce Muscle Breakdown
- Upregulates Anabolic Signaling Increase Muscle Protein Synthesis
- Reduces DOMS Delayed Onset Muscle Soreness
- Enhances Recovery
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WHAT IS HMB
Hydroxy Methylbutyrate HMB is an isolated metabolite of the protein synthesis activating Essential Amino Acid EAA , Leucine
The primary utility of HMB in the body is to inhibit the catabolism of muscle tissue
HMB VS LEUCINE
Gram for gram, literature suggests that HMB is 20x more potent than Leucine at inhibiting muscle breakdown
1 3 grams of HMB is seen as equivalent to 20 C60g of leucine supplementation for this purpose
An individual would need to consume over 600 g of high quality protein to obtain the amount of leucine 60 grams necessary to produce the typical 3 g daily dosage of HMB used in human studies
This doesn t mean throw your EAA s in the garbage and start pounding HMB, they each may have their own individual use case
For the purpose of muscle protein synthesis, HMB and leucine are fairly equivalent, but in the context of attenuating muscle loss, that s where HMB appears to shine in its application
HOW DOES IT WORK
HMB has been shown to result in a net positive balance of skeletal muscle protein turnover partly through stimulation of protein synthesis, but primarily via the attenuation of protein degradation
WHEN DOES IT MAKE SENSE TO SUPPLEMENT HMB
HMB excels during times when the risk of muscle catabolism is elevated
This can include bodybuilding prep, low protein diets, general caloric restriction, high intensity training, aging, high stress, fasting, periods of bed rest, illness, injuries, etc
Literature suggests that HMB may attenuate muscle loss and exercise induced muscle damage e g DOMS amp; damage from high intensity training while also augmenting muscle protein synthesis, strength, and body composition
If you are young, already consume enough protein, and are a well trained individual, the benefits of HMB will likely be less pronounced, and it may not be useful altogether
For older individuals with elevated anabolic resistance, or those subjecting themselves to one, or several of the aforementioned catabolic environments, HMB may be a useful tool to maintain a net positive balance of protein turnover, reduce markers of muscle damage, and preserve hard earned muscle mass
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